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Role of Capsaicin in Oxidative Stress and Cancer, Hardcover by Srivastava, Sa...
- Item No : 365737242081
- Condition : Brand New
- Brand : No brand Info
- Seller : greatbookprices1
- Current Bid : US $123.30
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* Item Description
- Role of Capsaicin in Oxidative Stress and Cancer, Hardcover by Srivastava, Sanjay K. (EDT), ISBN 9400763166, ISBN-13 9789400763166, Brand New, Free shipping in the US
This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
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