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Multiple Testing Procedures and Applications to Genomics, Hardcover by Dudoit...
- Item No : 357346151652
- Condition : Brand New
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* Item Description
- Multiple Testing Procedures and Applications to Genomics, Hardcover by Dudoit, Sandrine; Van Der Laan, Mark J., ISBN 0387493166, ISBN-13 9780387493169, Brand New, Free shipping in the US
<p>This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.</p>
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